Best Bet: Los Angeles Rams -3.5 (-110)

Week 3 historically is super tough. Proceed with caution. That said, I’m going against one of my big tenets in the NFL: I’m backing a road divisional favorite. I’m on the Rams on Sunday mostly because I think the Cardinals are really bad. Yes, Kyler Murray can go into video game mode at any time. And it is scary when he can single-handedly make the defense chase him around the field for 10+ seconds. However, other than that, what would make anyone be on the Cardinals in this game? Their defense looks horrible, especially the secondary. I believe Matt Stafford can expose that weakness. While the Cards are a little better against the run, I don’t expect the Rams to be running too much here. On the offensive side of the ball, the skill position players for Arizona have been either hurt or underwhelming. The Rams have a massive coaching advantage here with McVay over Kingsbury. McVay is 6-1 vs. Kliff lifetime which includes the Wild Card drubbing this past January. No Hopkins. No Rondale Moore. I’m unimpressed. Also, after the Rams gave back a lead by sitting back on defense last week, I expect a full game effort in this one.

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Best Bet: Minnesota Vikings -6 (-110)

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Best Bet: Indianapolis Colts +5.5 (-110)