Arizona Cardinals +12.5 (-110)

Yea, this is a tough bet to make. But, you know what they say, the toughest bets to make are the ones that tend to cash. So, here we are. Look, I’m not going to bother with power rankings, matchups, or anything else here. I am aware that the Niners are power rated through the roof and the Cardinals are a bottom 5 team. I also know that San Fran needs to keep winning for a shot at the number one seed. However, this is all about situation. The Niners have just been blowing teams out week after week. They also have a pretty big game next week against the Ravens, that many feel is a SuperBowl preview. I just think that this is a divisional game, where Kyler can run around and make some stuff happen. This feels like a bit of a letdown spot for the Niners. Remember, when these two teams played earlier this year, the Niners did cover but BARELY. And that was against Josh Dobbs. Now, it’s Kyler and it’s on the road. I’m not saying I think Arizona has a shot to win here, I doubt it. But maybe the hope is they keep it within two scores.